1.1 BACKGROUND OF THE STUDY
Medicinal Plants have recently become of
great interest owing to their versatile applications. These plants are
considered as rich resources of ingredients which can be used in drug
development and synthesis. In many part of the world medicinal plant
have been used for antibacterial, antifungal and antiviral activities
for hundreds of years (Ali et al., 1998; Barhour et al., 2004; Yasunaka et al., 2005). More than 30% of the pharmaceutical preparations are based on plants (Shinwari and Khan,
1998). An increasing reliance on the use of these medicinal plants in
the industrialized societies has been traced to the extraction and
development of several drugs and chemotherapeutics from medicinal
Recent research has begun to reveal
impressive fact about the scale of the developed world dependence upon
medicinal plant and the monetary and social value that these usages
represent (Farnsworth et al., 1991). Researchers are
increasingly turning attention to medicinal plant and looking for new
leads to develop better drugs against diseases (Ibrahim 1997; Tower et al., 2001; Koshy et al.,
2009). They have identified number of compounds used in mainstream
medicine which were derived from ethnomedical plant source (Fabricant
and Farnsworth 2001).
According to World Health Organization
(WHO), medicinal plants would be the best source to obtain variety of
drugs. An estimate of 80% individuals from developed countries uses
traditional medicines, which has compounds derived from medicinal plant.
Most populations still rely on traditional medicines for their
psychological and physical health requirements (Rabe and VanStoden,
2000), since they cannot afford the products of Western pharmaceutical
industries (Salie et al., 1996). These medicinal plant possess
therapeutically properties which are useful in healing various diseases
and the advantage of these medicinal plant are natural (Kalemba et al.,
2003). These plants contain chemicals which are classified into primary
and secondary metabolites. The primary metabolites are widely
distributed in nature and are obtained from higher plants.
Plants generally produce many secondary
metabolites which provide definite physiological action on the human
body and these bioactive substances include alkaloids, steroids,
tannins, glycosides, volatile oils, fixed oils, resins, phenols and
flavonoids which are deposited in their specific parts such as leaves,
flowers, bark, seeds, fruits, root and are biosynthetically derived from
primary metabolite and constitute an important source of microbicide,
pesticide and many pharmaceutical drugs. These secondary metabolites
have been directly or indirectly playing an important role in the human
society to combat disease (Wink et al., 2005). Secondary
metabolites are frequently accumulated by plant in small quantities than
the primary metabolites (Karuppusamy, 2009). The most important of
these bioactive compounds of plants are alkaloids, flavonoids, tannins
and phenolic compounds (Edoga et al., 2005). Screening of these
medicinal plants for antimicrobial and elementological activities are
important for finding potential new compounds for therapeutic use.
1.2 AIM OF STUDY
- Establish the ethno medicinal claims on the aerial parts of ALCHORNEA CORDIFOLIA
- Characterize some compound(s) that may be responsible for the claimed ethno medicinal values.
1.3 OBJECTIVE OF THE STUDY
The purpose of this study is to
i. Determine the phytochemical ingredient contained in the plant
ii. Investigate the antimicrobial activity of the plant extracts.
1.4 SCOPE OF STUDY
This research is designed to screen alchornea cordifolia medicinal
plant obtained from Awo-omamma community, Imo state, Nigeria, verifying
the extent to which the medicinal plant can contribute to the treatment
of various diseases.
In this study, there will be an
investigation on the usage of this medicinal plant, through
phytochemical screening, antimicrobial studies . It will also be
evaluating the systematical screening of plant species with the purpose
of discovering new bioactive compounds which will be of great important
to chemistry and to pharmaceutical industry.
JUSTIFICATION OF STUDY
This study justifies the fact that
medicinal plants have a promising future because there are about half a
million plants around the world that are yet to be investigated. The
choice of Alchornea cordifolia is based on its vast medicinal
importance in Awo-omamma community of Imo State and other parts of the
South-East region of Nigeria..
Therefore, we have decided to screen the
plant to know its microbial potency, phytochemical and bioactive
constituents. This study will further help to clarify their role in the
treatment of present diseases and however aid as a light to the
synthesis of new drugs.
A Research proposal for investigation into ethno medicinal claims on the aerial parts of alchornea cordifolia:
Reviews: A Review on investigation into ethno medicinal claims on the aerial parts of alchornea cordifolia, investigation, into, ethno project topics, researchcub.info, project topic, list of project topics, research project topics, journals, books, Academic writer.
This research is designed to screen alchornea cordifolia medicinal plant obtained from Awo-omamma community, Imo state, Nigeria, verifying the extent to which the medicinal plant can contribute to the treatment of various diseases... bio-chemistry project topics
INVESTIGATION INTO ETHNO MEDICINAL CLAIMS ON THE AERIAL PARTS OF ALCHORNEA CORDIFOLIA