EVALUATION OF PHARMACOGNOSTICPARAMETERS AND HEPATOTOXIC EFFECTS OF EXTRACTSOF CASSYTHA FILIFORMIS LINN ON PARACETAMOL-INDUCED LIVER DISORDERS IN WISTER RATS

EVALUATION OF PHARMACOGNOSTICPARAMETERS AND HEPATOTOXIC EFFECTS OF EXTRACTSOF CASSYTHA FILIFORMIS LINN ON PARACETAMOL-INDUCED LIVER DISORDERS IN WISTER RATS


1,201 marked this research material reliable.
Call or whatsapp: +2347063298784 or email: info@allprojectmaterials.com
Department: pharmacy project topics | Type: Project Topics | Project Topics and Materials | List of Project Topics | Research Project Materials | Journals | Thesis | Articles | Online Project Materials | Business Plan | Final year project topic | Format: Ms Word and PDF | Attribute: Documentation Only | Pages: 65 Pages | Chapters: Complete Research work from Chapter 1 to 5; All chapters | Inclusive: Abstract, Preliminary Pages, Table of Contents and Appendices | Cost: ₦ 5,000.00


EVALUATION OF PHARMACOGNOSTICPARAMETERS AND HEPATOTOXIC EFFECTS OF EXTRACTSOF CASSYTHA FILIFORMIS LINN ON PARACETAMOL-INDUCED LIVER DISORDERS IN WISTER RATS

PROJECT TOPICS AND MATERIALS ON EVALUATION OF PHARMACOGNOSTICPARAMETERS AND HEPATOTOXIC EFFECTS OF EXTRACTSOF CASSYTHA FILIFORMIS LINN ON PARACETAMOL-INDUCED LIVER DISORDERS IN WISTER RATS


ABSTRACT

Cassytha filiformis, a leafless and perennial vine with small scales as a replacement of the leavesis currently being used in the treatment of various disease conditions including jaundice without standardization.Microscopical evaluation, chromatographic analysis (TLC, HPLC, LC-MS/MS), spectroscopic analyses (NMR, FTIR, MS) and hepathoprotective studies were carried out with the view to scientifically verify the potentials of this plant used in traditional medicine. The results revealed the presence of some diagnostic microscopical features such as paracytic stomata, unicellular covering trichomes with cystoliths, prismatic calcium oxalate crystals and annular xylem vessels. Quantitative physical constants include moisture contents (5.5 %), ash value (17 %), acid insoluble ash value (1 %), total tannins (27.3 %), swelling index (165 %), water, alcohol and oil extractive indices (20.6 %, 13.6 % and 1.6 % respectively). Trace metals detected in C. filiformis such as Fe (165.4279 ppm), Mn (14.4093 ppm) and Ni (2.7933 ppm) which are essential were higher than FAO/WHO (1984) permissible limit for edible plants. While others:Pb (0.0568 ppm) Zn (0.1094 ppm), Cd (0.0103 ppm) and Cu (0.0535 ppm) were found to be within the safety limit. Preliminary phytochemical screening of the plant signifies the presence of alkaloids, tannins, flavonoids, saponins and steroids Phytochemical constituents identified in ethyl acetate and methanol extracts of C. filiformis include 3,3,O-di-O-methyl ellagic acid, catechin, chalcone compounds, p-hydroxybenzoic acid, isorhamnetin 3-O-rutinoside or isorhamnetin 3-O-neohesperidoside, kaemferol 3 rutinoside and 2-{cyclohex-2-en-1-yl(hydroxyl)methyl}-3-hydroxy-4-(2-hydroxyethyl)-3-methyl- oxoprolinate while that of methanol fraction include 3,3,O-di-O-methyl etllagic acid, methy2-{cyclohex-2-ene-1-y(hydroxyl)methyl}-3hydroxy-4-(2-hydroxyethyl)-3-methyl-5-oxoprolinate, kaemferol 3 rutinoside, rutin and cathechinas revealed by the library search on LC-MS/MS. Other compounds β-sitosterol and stigmasterol wereisolated from petroleum ether extracts.The petroleum ether extract (500 mgkg-1) and methanol (500 and 1000 mgkg-1) exhibited hepatoprotection properties on wistar albino rats. These results could serve as bases for the use of the plant in traditional medicine for the prevention of liver disorders.

1.1 Introduction

The role of plants in the treatment of disease is exemplified by their employment in all the major systems of medicine irrespective of the underlying philosophical premise. As example, we have the western medicine with origin in Mesopotamia and Egypt, the Unani (Islamic) and the Ayurvedic (Hindu) system and in Western Asia and the Indian subcontinent and those of the Orient (China, Japan, Tibetetc.). There is a great wealth of knowledge concerning the medicinal,narcotic and other properties of plants that is still transmitted orally from generation to generation by tribal societies, particularly those of the tropical Africa, North and South America and the Pacific countries (Evans, 2009). These are areas containing the world’s greatest number of plant species, not found elsewhere, and with the westernization of so many of the people of these zones there is pressing need to record local knowledge before it is lost forever. In addition, with the extermination of plant species progressing at an alarming rate in certain regions, even before plant have been botanically recorded, much less studied chemically and pharmacologically, the need arises for increased efforts directed towards the conservation of gene pools (Evans, 2009).

Since plant taxa are defined by their morphology (more specifically on the morphology of the flowering parts), identification techniques have relied almost entirely on physical examination of the specimen. However, drying and powdering alters or destroys diagnostic features and the plant parts traded in commerce may not include the parts necessary for establishing botanical identity. Classical description in compendia reflect this approach with physical descriptions that include appearance, color, order, and fracture.

DOWNLOAD COMPLETE WORK FOR EVALUATION OF PHARMACOGNOSTICPARAMETERS AND HEPATOTOXIC EFFECTS OF EXTRACTSOF CASSYTHA FILIFORMIS LINN ON PARACETAMOL-INDUCED LIVER DISORDERS IN WISTER RATS


Additional Information

  • The Project Material is available for download.
  • The Research material is delivered within 15-30 Minutes.
  • The Material is complete from Preliminary Pages to References.
  • Well Researched and Approved for supervision.
  • Click the download button below to get the complete project material.

Frequently Asked Questions

In-order to give you the best service available online, we have compiled frequently asked questions (FAQ) from our clients so as to answer them and make your visit much more interesting.

We are proudly Nigerians, and we are well aware of fraudulent activities that has been ongoing in the internet. To make it well known to our customers, we are geniune and duely registered with the Corporate Affairs Commission of the republic of Nigeria. Remember, Fraudulent sites can NEVER post bank accounts or contact address which contains personal information. Free chapter One is always given on the site to prove to you that we have the material. If you are unable to view the free chapter 1 send an email to info@researchcub.info with the subject head "FREE CHAPTER 1' plus the topic. You will get a free chapter 1 within an hour. You can also check out what our happy clients have to say.


Students are always advised to use our materials as guide. However, if you have a different case study, you may need to consult one of our professional writers to help you with that. Depending on similarity of the organization/industry you may modify if you wish.


We have professional writers in various disciplines. If you have a fresh topic, just click Hire a Writer or click here to fill the form and one of our writers will contact you shortly.


Yes it is a complete research project. We ensure that our client receives complete project materials which includes chapters 1-5, full references, questionnaires/secondary data, etc.


Depending on how fast your request is acknowledged by us, you will get the complete project material withing 15-30 minutes. However, on a very good day you can still get it within 5 minutes!

What Clients Say

Our Researchers are happy, see what they are saying. Share your own experience with the world.
Be polite and honest, as we seek to expand our business and reach more people. Thank you.

A Research proposal for evaluation of pharmacognosticparameters and hepatotoxic effects of extractsof cassytha filiformis linn on paracetamol-induced liver disorders in wister rats :
Reviews: A Review on evaluation of pharmacognosticparameters and hepatotoxic effects of extractsof cassytha filiformis linn on paracetamol-induced liver disorders in wister rats , evaluation, pharmacognosticparameters, hepatotoxic project topics, researchcub.info, project topic, list of project topics, research project topics, journals, books, Academic writer.
The role of plants in the treatment of disease is exemplified by their employment in all the major systems of medicine irrespective of the underlying philosophical premise. As example, we have the western medicine with origin in Mesopotamia and Egypt, the Unani (Islamic) and the Ayurvedic (Hindu) system and in Western Asia and the Indian subcontinent and those of the Orient (China, Japan, Tibetetc.). There is a great wealth of knowledge concerning the medicinal,narcotic and other properties of plants that is still transmitted orally from generation to generation by tribal societies, particularly those of the tropical Africa, North and South America and the Pacific countries (Evans, 2009). These are areas containing the world’s greatest number of plant species, not found elsewhere, and with the westernization of so many of the people of these zones there is pressing need to record local knowledge before it is lost forever. In addition, with the extermination of plant species progressing at an alarming rate in certain regions, even before plant have been botanically recorded, much less studied chemically and pharmacologically, the need arises for increased efforts directed towards the conservation of gene pools (Evans, 2009)... pharmacy project topics

EVALUATION OF PHARMACOGNOSTICPARAMETERS AND HEPATOTOXIC EFFECTS OF EXTRACTSOF CASSYTHA FILIFORMIS LINN ON PARACETAMOL-INDUCED LIVER DISORDERS IN WISTER RATS

Project Information

Share Links

Download Post (MsWord)
Download Post (PDF)

Search for Project Topics

Project topics in Departments

How much does it cost to hire a writer in Nigeria?

Looking for Professional Approach and Quality Research Services ?

Estimating the cost of research writing in Nigeria: Freelance writers in Nigeria may charge anywhere from ₦5,000 to ₦50,000 or more per project, depending on the factors mentioned earlier. SEO-focused content may be on the higher end of this range due to the additional skills and research involved. For a more accurate estimate, it's recommended to reach out with us, discuss your specific requirements, and request a quote based on the scope of your project. Prices can vary, so getting personalized quotes will help you determine the cost more precisely.

Undergraduate Project Topics, economics project topics, marketing project topics, business administration project topics, engineering project topics, computer science project topics, banking & finance project topics, education project topics, law project topics, sciences project topics, public administration project topics, political science project topics, mathematics project topics, medical science project topics, mass communication project topics, research projects, geology project topics, marketing project topics, agriculture project topics, Browse Thousands of Final Year Project Topics, hire a writer, Research Works and Materials, Project topics and materials in Nigeria, Undergraduate Project Topics, Research Works and Materials, research topics, research project materials, complete project materials, computer science project material, free project topics, complete projects, accounting topics, small business topics, entrepreneurship topics, project materials, Nigerian undergraduate projects, business administration projects, computer science topics and projects, MBA Nigerian project topics, human resources, small businesses, entrepreneurship projects, economics projects, impacts projects, effect projects, university projects, polytechnic projects, investigate projects, political science projects, mass communication projects, project topics, human resource projects, education projects, French topics, project analysis, French projects, project tips, project abstract, project proposals, project bibliography, project reference, project seminar, forex, TSA, treasury single account, currency, naira, devaluation, undergraduate projects, final project research, marketing project topics, statistics project topics, mathematics project topics, statistics, mathematics, research projects, project thesis, labour force theses, NCE, OND, HND, BTECH, BSC, MBA, MSC, English projects, linguistic project topics, Free Project topics and materials in Nigeria, research topics, reseach project materials, computer science project material, free, complete, accounting topics, small business topics, materials, nigeria projects, business administration projects, computer science topics and projects, MBA nigeria project topics, human resources, small business, entrepreneurship projects, economics projects, impact projects, effects projects, training, budgets, ghana, university, polytechnic, browse Free project materials and topics in Nigeria, accounting and finance project materials, business administration project materials and topics, human resources, entrepreneurship, computer science and engineering project materials and topics, Accounting project topics, Accounting project topics and materials, Agricultural Economics Project Topics and Materials, Agricultural Science Projects topics and materials, All Project topics and materials, Architecture Project topics and materials, Aviation project topics and materials, Banking & Finance Projects topics and materials, Biology project and materials, Building project topics and materials, Business Administration & Management Projects topics and materials, Chemical Engineering Project Topics and materials, Civil Engineering Projects topics and materials, Communication & mass communication art project topics and materials, Computer Engineering Project Topics and materials, Computer Science Projects topics and materials, Criminology project topics and materials, Economics Research Projects topics and materials, Education Project Topics and Materials, Electrical Engineering Projects and materials, English Education & English Language Project topics and materials, Food Science project topics and materials, Geology Project Topics and materials, Guidance Counseling Project Topics and materials, History project topics and materials, Home Economics Project Topics and Materials, Human Resource Projects topics and Materials, Industrial Chemistry Projects topics and materials, Insurance Projects topics and materials, Law project topics and materials, Library and information science project topics and materials, Marine and Transport management project topics and materials, Marketing Projects topics and materials, Mathematics project topics and materials, Medical Sciences Project Topics and materials, Microbiology project topics and materials, Nursing and Midwifery project topics, Nursing and Midwifery project topics and materials, Optometry or nursing project topics and materials, Petroleum Engineering project topics and materials, Pharmacy project topics and materials, Philosophy project topics and materials, Photography project topics and materials, Physical and Health Education project topics and materials, Physiology project topics and materials, Political science project topics and materials, Project topics and materials, Psychology project topics and materials, Random project, Religious and Cultural Studies Project Topics and Materials, Sociology and Anthropology Project topics and materials, Sociology Project Topics and materials, Tourism project topics and materials, Vocational education project topics and materials. Project Topics: List of Project Topics | evaluation of pharmacognosticparameters and hepatotoxic effects of extractsof cassytha filiformis linn on paracetamol-induced liver disorders in wister rats | evaluation | pharmacognosticparameters | hepatotoxic Project Topics | researchcub.info